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polyclonal goat anti plexind1 antibody  (R&D Systems)


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    R&D Systems polyclonal goat anti plexind1 antibody
    Down-regulation of striatonigral-enriched genes in Isl1 mutant brains at E18.5. SP immunoreactivity (A and A′) is significantly decreased in the striatum (St) (A′) and substantia nigra (SN) (D′) of Isl1 mutant mice. A similar reduction of <t>plexinD1</t> immunoreactivity is found in the mutant St (B and B′) and SN (E and E′). D1R immunoreactivity is disorganized in the mutant St (C and C′) and dramatically decreased in SN (F and F′). (G) qRT-PCR analyses show a consistent reduction of striatonigral-enriched genes, including Chrm4, Slc35d3, PlexinD1, SP, and Pdyn, in Isl1 mutant St. A trend of a decrease in Mef2c is noted. n = 4. *P < 0.05; ***P < 0.001. (Scale bar: A–F′, 100 μm.)
    Polyclonal Goat Anti Plexind1 Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyclonal+goat+anti+plexind1+antibody/Plexin+D1+Antibody/pmc03890800-448-129-134
    Average 92 stars, based on 3 article reviews
    polyclonal goat anti plexind1 antibody - by Bioz Stars, 2026-09
    92/100 stars

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    1) Product Images from "Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity"

    Article Title: Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    doi: 10.1073/pnas.1319138111

    Down-regulation of striatonigral-enriched genes in Isl1 mutant brains at E18.5. SP immunoreactivity (A and A′) is significantly decreased in the striatum (St) (A′) and substantia nigra (SN) (D′) of Isl1 mutant mice. A similar reduction of plexinD1 immunoreactivity is found in the mutant St (B and B′) and SN (E and E′). D1R immunoreactivity is disorganized in the mutant St (C and C′) and dramatically decreased in SN (F and F′). (G) qRT-PCR analyses show a consistent reduction of striatonigral-enriched genes, including Chrm4, Slc35d3, PlexinD1, SP, and Pdyn, in Isl1 mutant St. A trend of a decrease in Mef2c is noted. n = 4. *P < 0.05; ***P < 0.001. (Scale bar: A–F′, 100 μm.)
    Figure Legend Snippet: Down-regulation of striatonigral-enriched genes in Isl1 mutant brains at E18.5. SP immunoreactivity (A and A′) is significantly decreased in the striatum (St) (A′) and substantia nigra (SN) (D′) of Isl1 mutant mice. A similar reduction of plexinD1 immunoreactivity is found in the mutant St (B and B′) and SN (E and E′). D1R immunoreactivity is disorganized in the mutant St (C and C′) and dramatically decreased in SN (F and F′). (G) qRT-PCR analyses show a consistent reduction of striatonigral-enriched genes, including Chrm4, Slc35d3, PlexinD1, SP, and Pdyn, in Isl1 mutant St. A trend of a decrease in Mef2c is noted. n = 4. *P < 0.05; ***P < 0.001. (Scale bar: A–F′, 100 μm.)

    Techniques Used: Mutagenesis, Quantitative RT-PCR

    Related Articles

    Incubation:

    Article Title: Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity
    Article Snippet: .. Sections were incubated with the following primary antibodies overnight at room temperature: polyclonal rabbit anti-AC3 antibody (1:1,000; Cell Signaling), monoclonal mouse anti–β-gal antibody (1:1,000; Boehringer Mannheim), monoclonal rat anti-BrdU antibody (1:500; Accurate), monoclonal mouse anticalbindin antibody (1:1,000; Swant), monoclonal mouse anticalretinin antibody (1:1,000; Chemicon), polyclonal goat anti-ChAT antibody (1:200; Chemicom), polyclonal goat anti-D1R antibody (1:2,000; Frontier Institute), polyclonal rabbit anti-Isl1 antibody (1:2,000; kindly provided by S. Pfaff, Salk Institute, San Diego, CA), monoclonal 3A4 or 4D5 mouse anti-Isl1 antibody (1:100; Developmental Studies Hybridoma Bank), polyclonal rabbit anti–Met-Enk antibody (1:5,000; ImmunoStar), polyclonal chicken anti-c-myc antibody (1:1,000; Novus), monoclonal mouse anti-Nkx2.1 antibody (1:200; NeoMarkers), monoclonal mouse antineuronal NOS antibody (1:2,000; Sigma), polyclonal rabbit anti-MOR1 antibody (1:2,000; ImmunoStar), monoclonal rat anti–OL-pc antibody (1:1,000) ( 22 ), monoclonal mouse antiparvalbumin antibody (1:1,000; Sigma), polyclonal goat anti-plexinD1 antibody (1:1,000; R&D Systems), polyclonal rabbit anti-pH3 antibody (1:1,000; Millipore), and polyclonal rabbit anti-SP antibody (1:3,000; Eugene Tech, Inc.). ..



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    polyclonal goat anti plexind1 antibody  (R&D Systems)
    92
    R&D Systems polyclonal goat anti plexind1 antibody
    Down-regulation of striatonigral-enriched genes in Isl1 mutant brains at E18.5. SP immunoreactivity (A and A′) is significantly decreased in the striatum (St) (A′) and substantia nigra (SN) (D′) of Isl1 mutant mice. A similar reduction of <t>plexinD1</t> immunoreactivity is found in the mutant St (B and B′) and SN (E and E′). D1R immunoreactivity is disorganized in the mutant St (C and C′) and dramatically decreased in SN (F and F′). (G) qRT-PCR analyses show a consistent reduction of striatonigral-enriched genes, including Chrm4, Slc35d3, PlexinD1, SP, and Pdyn, in Isl1 mutant St. A trend of a decrease in Mef2c is noted. n = 4. *P < 0.05; ***P < 0.001. (Scale bar: A–F′, 100 μm.)
    Polyclonal Goat Anti Plexind1 Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyclonal+goat+anti+plexind1+antibody/Plexin+D1+Antibody/pmc03890800-448-129-134
    Average 92 stars, based on 1 article reviews
    polyclonal goat anti plexind1 antibody - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier

    Image Search Results


    Down-regulation of striatonigral-enriched genes in Isl1 mutant brains at E18.5. SP immunoreactivity (A and A′) is significantly decreased in the striatum (St) (A′) and substantia nigra (SN) (D′) of Isl1 mutant mice. A similar reduction of plexinD1 immunoreactivity is found in the mutant St (B and B′) and SN (E and E′). D1R immunoreactivity is disorganized in the mutant St (C and C′) and dramatically decreased in SN (F and F′). (G) qRT-PCR analyses show a consistent reduction of striatonigral-enriched genes, including Chrm4, Slc35d3, PlexinD1, SP, and Pdyn, in Isl1 mutant St. A trend of a decrease in Mef2c is noted. n = 4. *P < 0.05; ***P < 0.001. (Scale bar: A–F′, 100 μm.)

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity

    doi: 10.1073/pnas.1319138111

    Figure Lengend Snippet: Down-regulation of striatonigral-enriched genes in Isl1 mutant brains at E18.5. SP immunoreactivity (A and A′) is significantly decreased in the striatum (St) (A′) and substantia nigra (SN) (D′) of Isl1 mutant mice. A similar reduction of plexinD1 immunoreactivity is found in the mutant St (B and B′) and SN (E and E′). D1R immunoreactivity is disorganized in the mutant St (C and C′) and dramatically decreased in SN (F and F′). (G) qRT-PCR analyses show a consistent reduction of striatonigral-enriched genes, including Chrm4, Slc35d3, PlexinD1, SP, and Pdyn, in Isl1 mutant St. A trend of a decrease in Mef2c is noted. n = 4. *P < 0.05; ***P < 0.001. (Scale bar: A–F′, 100 μm.)

    Article Snippet: Sections were incubated with the following primary antibodies overnight at room temperature: polyclonal rabbit anti-AC3 antibody (1:1,000; Cell Signaling), monoclonal mouse anti–β-gal antibody (1:1,000; Boehringer Mannheim), monoclonal rat anti-BrdU antibody (1:500; Accurate), monoclonal mouse anticalbindin antibody (1:1,000; Swant), monoclonal mouse anticalretinin antibody (1:1,000; Chemicon), polyclonal goat anti-ChAT antibody (1:200; Chemicom), polyclonal goat anti-D1R antibody (1:2,000; Frontier Institute), polyclonal rabbit anti-Isl1 antibody (1:2,000; kindly provided by S. Pfaff, Salk Institute, San Diego, CA), monoclonal 3A4 or 4D5 mouse anti-Isl1 antibody (1:100; Developmental Studies Hybridoma Bank), polyclonal rabbit anti–Met-Enk antibody (1:5,000; ImmunoStar), polyclonal chicken anti-c-myc antibody (1:1,000; Novus), monoclonal mouse anti-Nkx2.1 antibody (1:200; NeoMarkers), monoclonal mouse antineuronal NOS antibody (1:2,000; Sigma), polyclonal rabbit anti-MOR1 antibody (1:2,000; ImmunoStar), monoclonal rat anti–OL-pc antibody (1:1,000) ( 22 ), monoclonal mouse antiparvalbumin antibody (1:1,000; Sigma), polyclonal goat anti-plexinD1 antibody (1:1,000; R&D Systems), polyclonal rabbit anti-pH3 antibody (1:1,000; Millipore), and polyclonal rabbit anti-SP antibody (1:3,000; Eugene Tech, Inc.).

    Techniques: Mutagenesis, Quantitative RT-PCR